Arthropathy – Differential Diagnosis

Red flags
  • Hot/painful/swollen joint with little movement
  • Trauma or bleeding disorder
  • Systemic symptoms (fever and weight loss)
  • Rest pain or nocturnal pain
  • Associated weakness and deformities
  • Local skin infections
Investigations to consider
  • FBC, CRP/ESR
  • U&Es, LFTs, Serum uric acid
  • Auto antibody screen, Rheumatoid factor
  • PSA
  • Viral screen
  • Mantoux test
  • Joint X-ray
  • CXR
  • Bone scan
  • Joint aspirate
  • Synovial biopsy

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